When a person swallows, this muscle relaxes to let food pass from the esophagus to the stomach. It normally stays closed at other times to keep stomach contents from flowing back into the esophagus.
However, in people who have a condition known as GERD, the LES stays open longer than it should, allowing stomach contents to flow back into the esophagus, and irritating the esophageal lining tissues. This can not only result in symptoms such as heartburn, but also can worsen asthma symptoms.

