Source: American Academy of Allergy, Asthma and Immunology
Ragweed is a weed that grows freely almost everywhere in the United States. It is most common, though, in rural areas of the eastern and Midwestern states, where the soil is bare of other vegetation, such as vacant lots and along roadways and river banks. Each plant survives only one season but puts out as many as 1 billion grains of pollen in that time.
Of people who are allergic to plant pollen, fully three-quarters — or 75 percent — are allergic to ragweed pollen. If you have ragweed allergy, there's not a lot you can do to cure your condition. There are, however, steps you can take to reduce the frequency and severity of your symptoms.
NOTE: People who have ragweed allergy are also at a higher risk for a condition known as oral allergy syndrome (OAS). Some people call this "pollen-food allergy."

